BRI member leads study showing how a molecular receptor helps restore brain function after 'silent stroke'
S. Thomas Carmichael, M.D., Ph.D., professor of neurology at the David Geffen School of Medicine, is senior author of a five year study that shows how the brain can be repaired and brain function recovered after a stroke in animals.
The discovery could have important implications for treating a mind-robbing condition known as a white matter stroke, which is a major form of dementia. "Despite how common and devastating white matter stroke is, there has been little understanding of how the brain responds and if it can recover," Dr. Carmichael said. "By studying the mechanisms and limitations of brain repair in this type of stroke, we will be able to identify new therapies to prevent disease progression and enhance recovery."
The study was published in the Proceedings of the National Academy of Sciences (December 27th, 2016).
More details here.
Image left: New brain cells replace those destroyed by stroke in animals: immature cells are green, more mature cells are red and fully mature cells are orange.